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  • 产品名称：RAD17Homolog(S.Pombe)(RAD17)(N-Term)Peptide

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简单介绍：
RAD17Homolog(S.Pombe)(RAD17)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-RAD17 Homolog (S. Pombe) (RAD17) (N-Term) antibody (ABIN2779342)
Sequence MNQVTDWVDP SFDDFLECSG VSTITATSLG VNNSSHRRKN GPSTLESSRF
Characteristics This is a synthetic peptide designed for use in combination with anti-RAD17 Antibody(ARP30546_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.

Alias Symbols: CCYC, FLJ41520, HRAD17, R24L, RAD17SP, RAD24

Protein Interaction Partner: ATM,ATR,HUS1,MCM7,NHP2L1,POLE,RAD1,RAD9A,RAD9B,RFC4,ALK,ATM,ATR,CLSPN,FOXO3,H2AFX,HUS1,NHP2L1,POLE,POLE2,POLE3,POLE4,PRKDC,RAD1,RAD9A,RAD9B,RFC1,RFC2,RFC3,RFC4,RFC5,USP20

Protein Size: 670
Molecular Weight 76 kDa
Gene ID 5884
NCBI Accession NM_002873, NP_002864
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.