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  • 产品名称：POUClass3Homeobox3(POU3F3)(N-Term)Peptide

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简单介绍：
POUClass3Homeobox3(POU3F3)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-POU3F3 antibody (POU Class 3 Homeobox 3) (N-Term) (ABIN2777730)
Characteristics This is a synthetic peptide designed for use in combination with anti-POU3F3 antibody (Catalog #: ARP33062_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].

Alias Symbols: BRN1, OTF8

Protein Interaction Partner: POU3F4,PPP1R15A,SOX10,SOX11,SOX8,POU3F4

Protein Size: 500
Molecular Weight 50 kDa
Gene ID 5455
NCBI Accession NM_006236, NP_006227
UniProt P20264
Research Area Transcription Factors, Chromatin and Nuclear Signaling
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.