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  • 产品名称：omega-conotoxinGVIA

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  • 产品厂商：Smartox-Biotech
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简单介绍：
omega-conotoxinGVIA
详情介绍：
Purpose omega-conotoxin GVIA blocks Cav2.2
Sequence H-Cys1-Lys-Ser-Hyp-Gly-Ser-Ser-Cys8-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys15-Cys16-Arg-Ser-Cys19-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys26-Tyr-NH2Hyp: hydroxypro line(Disulfide bonds between Cys1-Cys16, Cys8-Cys19 and Cys15-Cys26)
Background Omega-conotoxin GVIA has been isolated from the venom of the cone Conus eographus. Omega-conotoxin GVIA acts at presynaptic membranes. It binds and blocks specifically Cav2.2 channel with an ED50 of 68pM.
Molecular Weight 3036.05 Da
CAS-No 106375-28-4
Restrictions For Research Use only