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  • 产品名称:anti-PrelaminA(C-Term)antibody

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简单介绍:
anti-PrelaminA(C-Term)antibody
详情介绍:
Immunogen Prelamin A C-terminus peptide
Specificity Antiprelamin A polyclonal antibody detects fulllenght prelamin A which has not yet undergone proteolytic steps both in its nonfarnesylated and in its farnesylated form. The farnesylated form of fulllenght prelamin A is labelled by the antibody with lower efficiency. The antibody does not cross react with mature lamin A.
Characteristics Several laminopathies are characterized by an anomalous accumulation of prelamin A, the lamin A precursor. This polyclonal antibody is able to detect full-length prelamin A, while it does not recognize either mature lamin A or cleaved prelamin A intermediates.
Purification Purified by protein A affinity chromatography and conjugated by NHS-biotin.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Supplied in PBS and 0.05 % v/v glycerol.
Storage 4 °C