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  • 产品名称：anti-BCL2antibody(B-CellCLL/lymphoma2)(AA49-76)

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  • 产品厂商：NSJBio
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简单介绍：
anti-BCL2antibody(B-CellCLL/lymphoma2)(AA49-76)
详情介绍：
Immunogen A portion of amino acids 49-76 from the human protein was used as the immunogen for this anti-Bcl-2 antibody.
Isotype Ig Fraction
Purification Antigen affinity purified
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UniProt P10415
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Titration of the anti-Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the anti-Bcl-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 49-76) antibody (ABIN3030096) Anti-Bcl-2 antibody western blot analysis in HeLa lysate