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  • 产品名称:anti-BCL2antibody(B-CellCLL/lymphoma2)(AA87-116)

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  • 产品厂商:NSJBio
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简单介绍:
anti-BCL2antibody(B-CellCLL/lymphoma2)(AA87-116)
详情介绍:
Immunogen A portion of amino acids 87-116 from the human protein was used as the immunogen for this BCL-2 antibody.
Isotype Ig Fraction
Cross-Reactivity (Details) Expected species reactivity: Bovine,Hamster,Mouse,Rat
Purification Antigen affinity purified
Alternative Name BCL-2 (BCL2 Antibody Abstract)
Background This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
UniProt P10415
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Titration of the BCL-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the BCL-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
 image for anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 87-116) antibody (ABIN3030095) BCL-2 antibody pre-incubated without (Lane 1) and with (2) blocking peptide in 293 ly...