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  • 产品名称:anti-PSMA1antibody(Proteasome(Prosome,Macropain)Subunit,alphaType,1)(AA234-262)

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  • 产品厂商:NSJBio
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简单介绍:
anti-PSMA1antibody(Proteasome(Prosome,Macropain)Subunit,alphaType,1)(AA234-262)
详情介绍:
Immunogen A portion of amino acids 234-262 from the human protein was used as the immunogen for this PSMA1 antibody.
Isotype Ig Fraction
Cross-Reactivity (Details) Expected species reactivity: Bovine,Primate
Purification Antigen affinity purified
Alternative Name PSMA1 (PSMA1 Antibody Abstract)
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
UniProt P25786
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Application Notes Titration of the PSMA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the PSMA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 1 (PSMA1) (AA 234-262) antibody (ABIN3032353) PSMA1 antibody western blot analysis in A2058 lysate.