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  • 产品名称：anti-TSG101antibody(TumorSusceptibilityGene101)(AA1-30)

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  • 产品厂商：NSJBio
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简单介绍：
anti-TSG101antibody(TumorSusceptibilityGene101)(AA1-30)
详情介绍：
Immunogen A portion of amino acids 1-30 from the human protein was used as the immunogen for this TSG101 antibody.
Isotype Ig Fraction
Purification Purified
Alternative Name TSG101 (TSG101 Antibody Abstract)
Background TSG101 is a component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. [UniProt]
UniProt Q99816
Research Area Cancer, Cell Cycle
Application Notes Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS,?pH 7.4, with 0.09?% sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the TSG101 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
Immunohistochemistry (IHC) image for anti-Tumor Susceptibility Gene 101 (TSG101) (AA 1-30) antibody (ABIN3029402) IHC analysis of FFPE human breast carcinoma tissue stained with the TSG101 antibody.
Western Blotting (WB) image for anti-Tumor Susceptibility Gene 101 (TSG101) (AA 1-30) antibody (ABIN3029402) Western blot testing of TSG101 antibody and mouse kidney tissue lysate. Predicted mol...