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  • 产品名称：anti-LDLRantibody(LowDensityLipoproteinReceptor)(AA391-419)

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  • 产品厂商：NSJBio
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简单介绍：
anti-LDLRantibody(LowDensityLipoproteinReceptor)(AA391-419)
详情介绍：
Immunogen A portion of amino acids 391-419 from the human protein was used as the immunogen for this LDLR antibody.
Isotype Ig Fraction
Cross-Reactivity (Details) Expected species reactivity: Rat,Pig,Rabbit,Hamster,Xenopus
Purification Antigen affinity purified
Alternative Name LDLR (LDLR Antibody Abstract)
Background The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
UniProt P01130
Pathways Hepatitis C
Application Notes Titration of the LDLR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the LDLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
Flow Cytometry (FACS) image for anti-Low Density Lipoprotein Receptor (LDLR) (AA 391-419) antibody (ABIN3031637) LDLR antibody flow analysis of MCF-7 cells (bottom histogram) compared to a negative ...
Western Blotting (WB) image for anti-Low Density Lipoprotein Receptor (LDLR) (AA 391-419) antibody (ABIN3031637) Western blot analysis of LDLR antibody and mouse lung tissue lysate. Predicted size: ...