Alternative Name
|
TLR7 (TLR7 Antibody Abstract)
|
Background
|
Toll like receptor 7 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). [UniProt]
|
UniProt
|
Q9NYK1
|
Research Area
|
Immunology, Innate Immunity, Transcription Factors, Signaling, Inflammation
|
Pathways
|
TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
|