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产品名称:anti-AngiotensinIConvertingEnzyme2antibody(AngiotensinIConvertingEnzyme(Peptidy
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产品厂商:NSJBio
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简单介绍:
anti-AngiotensinIConvertingEnzyme2antibody(AngiotensinIConvertingEnzyme(Peptidyl-DipeptidaseA)2)
详情介绍:
Product Details anti-Angiotensin I Converting Enzyme 2
Antibody
Product Details anti-Angiotensin I Converting Enzyme 2 Antibody
Immunogen
Purified His-tagged protein was used to produced this monoclonal ACE2 antibody.
Clone
881CT16-4-4
Isotype
IgM, kappa
Purification
Purified
Target Details Angiotensin I Converting Enzyme 2
Target Details Angiotensin I Converting Enzyme 2
Alternative Name
ACE2 (ACE2 Antibody Abstract)
Background
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
UniProt
Q9BYF1
Research Area
Metabolism, Enzymes, Serum/Plasma Proteins
Pathways
ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Application Details
Application Details
Application Notes
Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Handling
Handling
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Images
Images
Supplier Images
ACE2 antibody western blot analysis in (1) 293, (2) K562, (3) MCF-7, (4) SK-BR-3, (5)...
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ACE2 antibody western blot analysis in (1) 293, (2) K562, (3) MCF-7, (4) SK-BR-3, (5) T47D, (6) MDA-MB-453 cell line and (7) mouse testis tissue lysate. Predicted molecular weight: 90-100 kDa.
ACE2 antibody western blot analysis in (1) 293, (2) K562, (3) MCF-7, (4) SK-BR-3, (5) T47D, (6) MDA-MB-453 cell line and (7) mouse testis tissue lysate. Predicted molecular weight: 90-100 kDa.