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  • 产品名称：anti-AngiotensinIConvertingEnzyme2antibody(AngiotensinIConvertingEnzyme(Peptidy

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  • 产品厂商：NSJBio
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简单介绍：
anti-AngiotensinIConvertingEnzyme2antibody(AngiotensinIConvertingEnzyme(Peptidyl-DipeptidaseA)2)(AA140-172)
详情介绍：
Immunogen A portion of amino acids 140-172 from the human protein was used as the immunogen for this ACE2 antibody.
Isotype Ig Fraction
Purification Purified
Alternative Name ACE2 (ACE2 Antibody Abstract)
Background ACE2 is a carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. [UniProt]
UniProt Q9BYF1
Research Area Metabolism, Enzymes, Serum/Plasma Proteins
Pathways ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Application Notes Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS,?pH 7.4, with 0.09?% sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the ACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
Flow Cytometry (FACS) image for anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2 (ACE2) (AA 140-172) antibody (ABIN3029963) Flow cytometric analysis of HL-60 cells using ACE2 antibody (green) compared to a neg...
Immunohistochemistry (IHC) image for anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2 (ACE2) (AA 140-172) antibody (ABIN3029963) IHC analysis of FFPE human breast carcinoma tissue stained with the ACE2 antibody
Western Blotting (WB) image for anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2 (ACE2) (AA 140-172) antibody (ABIN3029963) Western blot analysis of lysate from human kidney tissue lysate using ACE2 antibody d...